Research Interests
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My research focuses on the intersection of functional nanomaterials with biochemistry and biomedicine. Specifically, I explore innovative techniques for probing, modifying, and controlling biological cells, with direct implications for cell therapeutics, cancer detection and treatment, bio-microplastics detection, and targeted drug delivery. My active research areas include:
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Advanced periodic nanostructures for the direct delivery of bioactive molecules to mammalian cells, as antibiofouling surfaces, and for the enhancement of LDI-Mass Spectroscopy.
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Nanoparticles fabricated largely from crystalline porous silicon nanoparticles for targeted drug delivery to specific human organs or tissue.
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Microfluidic systems for mechanical intracellular agent delivery, high-frequency (microwave) sensing of cell electrical permittivity (ε), and for sensing of bio-microplastics.
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Impedance cytometry and high-frequency electronic sensors for rapid flow-through measurements of cell electrical density (electrical permittivity) and micro-scale material characterization.
Publications
Secme, Arda, et al. "Dielectric Detection of Single Nanoparticles Using a Microwave Resonator Integrated with a Nanopore." ACS omega 9.7 (2024): 7827-7834.
Tefek, Uzay, et al. "Permittivity‐Based Microparticle Classification by the Integration of Impedance Cytometry and Microwave Resonators." Advanced Materials 35.46 (2023): 2304072.
Secme, Arda, et al. "High-resolution dielectric characterization of single cells and microparticles using integrated microfluidic microwave sensors." IEEE Sensors Journal 23.7 (2023): 6517-6529.